About loss of regularity and "blow up" of solutions for quasilinear parabolic systems.

Starting from sufficient conditions for regularity of weak solutions to quasilinear parabolic systems, uecessary conditions for loss of regularity are formulated. It is shown numerically that in some situations loss of regularity ("blow up") really happens accordingly to these conditions

Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release.

Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs). Whereas in bacteria, RF1 and RF2 promote termination at UAA/UAG and UAA/UGA stop codons, respectively, eukaryotes only depend on one RF (eRF1) to initiate peptide release at all three stop codons. Based on several structural as well as biochemical studies, interactions between mRNA, tRNA, and rRNA have been proposed to be required for stop codon recognition. In this study, the influence of these interactions was investigated by using chemically modified stop codons. Single functional groups within stop codon nucleotides were substituted to weaken or completely eliminate specific interactions between the respective mRNA and RFs. Our findings provide detailed insight into the recognition mode of bacterial and eukaryotic RFs, thereby revealing the chemical groups of nucleotides that define the identity of stop codons and provide the means to discriminate against noncognate stop codons or UGG sense codons

Integrative transcriptome and proteome analysis of the tube foot and adhesive secretions of the sea urchin paracentrotus lividus

IF/00006/2015/CP1276/CT0001 P 25404-B25 P 30347Echinoderms, such as the rock-boring sea urchin Paracentrotus lividus, attach temporarily to surfaces during locomotion using their tube feet. They can attach firmly to any substrate and release from it within seconds through the secretion of unknown molecules. The composition of the adhesive, as well as the releasing secretion, remains largely unknown. This study re-analyzed a differential proteome dataset from Lebesgue et al. by mapping mass spectrometry-derived peptides to a P. lividus de novo transcriptome generated in this study. This resulted in a drastic increase in mapped proteins in comparison to the previous publication. The data were subsequently combined with a differential RNAseq approach to identify potential adhesion candidate genes. A gene expression analysis of 59 transcripts using whole mount in situ hybridization led to the identification of 16 transcripts potentially involved in bioadhesion. In the future these data could be useful for the production of synthetic reversible adhesives for industrial and medical purposes.publishersversionpublishe

Beiträge zur Geschichte des Landkreises Regensburg 8

1200 Jahre Sünching - Beiträge zur Geschichte eine Gäubodengemeinde; Darin: Werner, Hannsjürgen: Die vor- und frühgeschichtliche Besiedlung der Gemeinde Sünching (S. 10); Spitzlberger, Georg: Ein römisches Landhaus im Raum Sünching (S. 15); Fendl, Josef: Die Ochsenstraße (S. 18); Fendl, Josef: Die ersten urkundlichen Nennungen Sünchings (S. 19); Fendl, Josef: Das älteste Sünchinger Denkmal (S. 21); Fendl, Josef: Die Sünchinger - Marschälle des Hochstifts Regensburg (S. 23); Fendl, Josef: Die Hofer und Staufer als Herren von Sünching (S. 25); Fendl, Josef: Eine Sünchinger Prachtbibel (S. 30); Fendl, Josef: Ein Sünchinger war Hofnarr der Fürstbischöfe von Passau (S. 32); Reichl, Josef: Die Seinsheimer in Sünching (S. 34); Fendl, Josef: Ein schreckliches halbes Jahr (1633/34) (S. 39); Fendl, Josef: Die Herrschaft Sünching (S. 40); Fendl, Josef: Die Sünchinger Sautonerl (S. 42); Fendl, Josef: Die Sünchinger haben wunderbare Hilf erlangt (S. 44); Hotter, Hans: Der Kreitmaier-Prozeß (S. 46); Prinz zu Sayn-Wittgenstein, Franz: Das Sünchinger Schloß (S. 51); Reichl, Josef, Die Sünchinger Kirchen (S. 57); Fendl, Josef: Die Brandkatastrophe von 1859 (S. 59); Fendl, Josef: Die Sünchinger Völkchen im vorigen Jahrhundert (S. 61); Fendl, Josef: Aus der Schulgeschichte Sünchings (S. 62); Jende, Herbert: Geschichtliche Entwicklung der Postanstalt Sünching (S. 68); Zeitler, Walther: Sünching war einmal Eisenbahnknotenpunkt (S. 71); Reichl, Josef: Sünchinger Flurnamen (S. 75); Hermes, Karl: Sünching (S. 79); Fendl, Josef: Die Sünchinger Wappen (S. 95); Zölch, Willi: Wußten Sie, dass ... (S. 96); Frank, Georg: Heimat Sünching (S. 98

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good